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Wiley Encyclopedia Of Chemical Biology

Author: Tadhg P. Begley
Publisher: Wiley
ISBN: 9780470470190
Size: 35.34 MB
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The first major reference at the interface of chemistry, biology, and medicine Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: Applications of chemical biology Biomolecules within the cell Chemical views of biology Chemistry of biological processes and systems Synthetic molecules as tools for chemical biology Technologies and techniques in chemical biology Some 300 articles range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the Wiley Encyclopedia of Chemical Biology builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.

Natural Products In Chemical Biology

Author: Natanya Civjan
Publisher: John Wiley & Sons
ISBN: 1118391829
Size: 31.48 MB
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Based on the award winning Wiley Encyclopedia of Chemical Biology, this book provides a general overview of the unique features of the small molecules referred to as "natural products", explores how this traditionally organic chemistry-based field was transformed by insights from genetics and biochemistry, and highlights some promising future directions. The book begins by introducing natural products from different origins, moves on to presenting and discussing biosynthesis of various classes of natural products, and then looks at natural products as models and the possibilities of using them in medicine.

Chemical Biology

Author: Natanya Civjan
Publisher: John Wiley & Sons
ISBN: 1118434501
Size: 53.42 MB
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An authoritative look at the application of chemicalbiology in drug discovery and development Based on the award-winning Wiley Encyclopedia of ChemicalBiology published in 2008, this book explores the role ofchemical biology in drug discovery and development. The first partof the book reviews key principles and techniques used in thedesign and evaluation of drug candidates. The second partelucidates biological mechanisms of certain diseases, illuminatingapproaches to investigate and target these diseases. Comprising carefully selected reprints from theEncyclopedia as well as new contributions from leadingscholars in the field, this book provides researchers in academiaand industry with important information to aid in the developmentof novel agents to treat disease. Self-contained articles cover avariety of essential topics, including: The design, development, and optimization of drugcandidates The pharmacokinetics and properties of drugs Drug transport and delivery Natural products and natural product models aspharmaceuticals Biological mechanisms underlying health and disease Treatment strategies for a range of diseases, from HIV toschizophrenia Chemical Biology is a top-notch guide and reference foranyone working in the areas of drug discovery and development,including researchers in chemical biology and other fields such asbiochemistry, medicine, and pharmaceutical sciences.

Wiley Encyclopedia Of Forensic Science

Author: Allan Jamieson
Publisher: John Wiley & Sons
ISBN: 0470018267
Size: 51.21 MB
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This A to Z encyclopedia provides a comprehensive, definitive, and up-to-date reference of the main areas of specialist and expert knowledge and skills used by those involved in all aspects of the forensic process, including, but not limited to, forensic scientists, doctors, practicing and academic lawyers, paralegals, police, crime scene investigators, analytical chemists, behavioral scientists and toxicologists. This five-volume set covers all topics which, either as part of an established forensic discipline or as a potentially useful emerging discipline, are of interest to those involved in the forensic process. This includes both the scientific methodology and the admissibility of evidence. The encyclopedia also provides case studies of landmark cases in the definition and practice of forensic science. Wiley Encyclopedia of Forensic Science presents all material on a level and in a style that makes it accessible to a wide range of readers. In particular, lawyers needing to better understand the key aspects of the science, and scientists who require a deeper insight into legal issues will find the encyclopedia an important resource, as will physical, biological and behavioral scientists who require background information on the most important aspects of each other’s areas of expertise.

Chemical Biology Of Natural Products

Author: David J. Newman
Publisher: CRC Press
ISBN: 1351643282
Size: 11.86 MB
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Chemical Biology of Natural Products This unique, long-awaited volume is designed to address contemporary aspects of natural product chemistry and its influence on biological systems, not solely on human interactions. The subjects covered include discovery, isolation and characterization, biosynthesis, biosynthetic engineering, pharmaceutical, and other applications of these compounds. Each chapter begins with a brief and simple introduction to the subject matter, and then proceeds to guide the reader towards the more contemporary, cutting-edge research in the field, with the contributing authors presenting current examples from their own work in order to exemplify key themes. Topics covered in the text include genome mining, heterologous expression, natural product synthesis, biosynthesis, glycosylation, chemical ecology, and therapeutic applications of natural products, both current and potential.

Nuclear Magnetic Resonance

Author: Krystyna Kamienska-Trela
Publisher: Royal Society of Chemistry
ISBN: 1849733732
Size: 79.18 MB
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Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive coverage of the literature on this topic.

Organische Chemie Der Biologischen Stoffwechselwege

Author: John McMurry
Publisher: Spektrum Akademischer Verlag
ISBN: 9783827416575
Size: 78.57 MB
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Oftmals mangelt es an einem Verständnis der interdisziplinären Natur von Chemie und Biologie. Dies liegt zum Teil daran, dass ein geeignetes Lehrbuch für das Grund- und Hauptstudium fehlt, das die Grundlagen hierfür schafft und als Basis für weitere Diskussionen dienen kann. Ein neues Buch von John McMurry und Tadhg Begley, prominenten Wissenschaftlern auf dem Gebiet der organischen Chemie und der mechanistischen Enzymologie, schließt elegant diese Lücke. Rongson Pongdee und Hung-wen Liu in Chemistry and Biology 2005 Vierfarbig, grundlegend, klar gegliedert, einzigartig - Für wen ist das vierfarbige Lehrbuch geeignet? Für Studenten im Grund- und Hauptstudium aus allen Bereichen der Bioorganischen Chemie und der Biologischen Chemie sowie der Chemischen Biologie und der Biochemie. - Sind Vorkenntnisse erforderlich? Nein, nur Grundkenntnisse in organischer Chemie. - Wie gliedert sich das Buch? Nach den wichtigsten biochemischen Stoffwechselwegen mit ihren Reaktionsmechanismen und der zugrunde liegenden molekularen Logik, nach denen die Natur die Moleküle des Lebens ineinander umwandelt. Die wichtigsten Stoffwechselwege der verschiedenen Hauptklassen von Biomolekülen (Lipide, Kohlenhydrate, Aminosäuren und Nucleotide) werden vorgestellt und Themen wie Ionisierungszustände, Stereochemie, Prochiralität und andere wesentliche Merkmale der Struktur und Reaktivität verständlich erklärt.