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Functioning Of Transmembrane Receptors In Signaling Mechanisms

Author: Ralph A. Bradshaw
Publisher: Academic Press
ISBN: 0123822122
Size: 54.60 MB
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A primary component of cell signaling research, this title covers the principal membrane-bound receptor families, including their structural organization. Written and edited by experts in the field, this book provides up-to-date research on transmembrane signaling entities and their initiating responses following extracellular stimulation. Articles written and edited by experts in the field Thematic volume covering effectors, cytosolic events, nuclear, and cytoplasmic events Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease

Transduction Mechanisms In Cellular Signaling

Author: Edward A. Dennis
Publisher: Academic Press
ISBN: 0123838622
Size: 80.86 MB
Format: PDF, ePub
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"Cell signaling, which is also often referred to as signal transduction or, in more specialized cases, transmembrane signaling, is the process by which cells communicate with their environment and respond temporally to external cues that they sense there. All cells have the capacity to achieve this to some degree, albeit with a wide variation in purpose, mechanism, and response. At the same time, there is a remarkable degree of similarity over quite a range of species, particularly in the eukaryotic kingdom, and comparative physiology has been a useful tool in the development of this field. The central importance of this general phenomenon (sensing of external stimuli by cells) has been appreciated for a long time, but it has truly become a dominant part of cell and molecular biology research in the past three decades, in part because a description of the dynamic responses of cells to external stimuli is, in essence, a description of the life process itself. This approach lies at the core of the developing fields of proteomics and metabolomics, and its importance to human and animal health is already plainly evident"--Provided by publisher.

Regulation Of Organelle And Cell Compartment Signaling

Author: Ralph A. Bradshaw
Publisher: Academic Press
ISBN: 0123822149
Size: 44.70 MB
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This must-have cell signaling title will appeal to researchers across molecular biology, biochemistry, cell biology and genetics. The articles are written and edited by experts in the field and emphasize signaling to and from intracellular compartments including transcriptional responses to cytoplasmic and nuclear signaling events, chromatin remodeling and stress responses, the regulation of endoplasmic reticulum function, control of cell cycle progression and apoptosis and the modulation of the activities of mitochondria and other organelles. Articles written and edited by experts in the field Thematic volume covering regulation of endoplasmic reticulum function, regulation of cell cycle progression, and quality control and assurance in mitochondrion events Up-to-date research on events in membrane proteins and proteins of intracellular matrix

Intercellular Signaling In Development And Disease

Author: Edward A. Dennis
Publisher: Academic Press
ISBN: 0123822165
Size: 25.20 MB
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Required reading for anyone involved in cell signaling research with articles written and edited by experts in the field. This title covers disease states such as lymphoid leukemia, breast cancer, pulmonary fibrosis, systemic sclerosis, andinflammatory bowel disease, along with up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease. Articles written and edited by experts in the field Thematic volume covering disease states such as lymphoid leukemia, breast cancer, pulmonary fibrosis, systemic sclerosis, and inflammatory bowel disease Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease

Foundations Of Anesthesia

Author: Hugh C. Hemmings
Publisher: Elsevier Health Sciences
ISBN: 0323037070
Size: 64.94 MB
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Accompanying CD-ROM ... "allows you to download figures into PowerPoint for electronic presentations." -- p. [4] of cover.

Histology And Cell Biology An Introduction To Pathology E Book

Author: Abraham L Kierszenbaum
Publisher: Elsevier Health Sciences
ISBN: 0323085881
Size: 16.75 MB
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Histology and Cell Biology: An Introduction to Pathology uses a wealth of vivid, full-color images to help you master histology and cell biology. Dr. Abraham L. Kierszenbaum presents an integrated approach that correlates normal histology with cellular and molecular biology, pathology, and clinical medicine throughout the text. A unique pictorial approach—through illustrative diagrams, photomicrographs, and pathology photographs—paired with bolded words, key clinical terms in red, and clinical boxes and "Essential Concepts" boxes that summarize important facts give you everything you need to prepare for your course exams as well as the USMLE Step 1. Access to studentconsult.com, with USMLE-style multiple-choice review questions, downloadable images, and online only references. Easily find and cross-reference information through a detailed table of contents that highlights clinical examples in red. Review material quickly using pedagogical features, such as Essential Concept boxes, bolded words, and key clinical terms marked in red, that emphasize key details and reinforce your learning. Integrate cell biology and histology with pathology thanks to vivid descriptive illustrations that compare micrographs with diagrams and pathological images. Apply the latest developments in pathology through updated text and new illustrations that emphasize appropriate correlations. Expand your understanding of clinical applications with additional clinical case boxes that focus on applying cell and molecular biology to clinical conditions. Effectively review concepts and reinforce your learning using new Concept Map flow charts that provide a framework to illustrate the integration of cell-tissue-structure-function within a clinical-pathology context.

Trp Ion Channel Function In Sensory Transduction And Cellular Signaling Cascades

Author: Wolfgang B. Liedtke, MD, PH.D.
Publisher: CRC Press
ISBN: 1420005847
Size: 35.35 MB
Format: PDF, Kindle
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Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of stimuli from both within and outside the cell body. How we sense heat and cold, how we taste food, how eggs are fertilized, how the heart expands and contracts is each dependent on the function of these channels. While no single book could possibly cover all the research being undertaken, TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades presents the most advanced compilation of work in this area to date. All 31 chapters are written by international pioneers working at the vanguard of TRP ion channel research. They explain much about the pivotal function and behavior of these channels, which are most exquisitely tuned to their specific tasks, and delve into how researchers are putting this knowledge to use in the development of novel pharmaceuticals, which may well prove effective in ameliorating treatment-resistant conditions including cancer, heart disease, inflammation, and immune system dysfunctions. Individual chapters shed light on selected topics of interest in the TRP arena, such as signal transduction in axonal path-finding, and in vascular, renal, and auditory functions, as well as pain. The text also covers subjects as diverse as mating and fertilization, inflammatory pain, and mechanisms of pheromone detection in mammals. While the book presents much new insight and explores findings that will be of interest to those involved with advanced research, it also includes significant background material for those looking to familiarize themselves with this exceptionally promising path of inquiry.

Sabiston Textbook Of Surgery E Book

Author: Courtney M. Townsend
Publisher: Elsevier Health Sciences
ISBN: 1455738085
Size: 42.39 MB
Format: PDF, ePub, Mobi
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Sabiston Textbook of Surgery is your ultimate foundation for confident surgical decision making. Covering the very latest science and data affecting your treatment planning, this esteemed medical reference helps you make the most informed choices so you can ensure the best outcome for every patient. Consult it on the go with online access at expertconsult.com, and get regular updates on timely new findings and advances. Overcome tough challenges, manage unusual situations, and avoid complications with the most trusted advice in your field. Prepare for tests and exams with review questions and answers online. Keep up with the very latest developments concerning abdominal wall reconstruction, tumor immunology and immunotherapy, peripheral vascular disease, regenerative medicine, liver transplantation, kidney and pancreas transplantation, small bowel transplantation, the continually expanding role of minimally invasive and robotic surgery, and many other rapidly evolving areas. Weigh your options by reviewing the most recent outcomes data and references to the most current literature.

Cell Signaling

Author: Wendell Lim
Publisher: Taylor & Francis
ISBN: 1317573625
Size: 40.12 MB
Format: PDF, Mobi
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Cell Signaling presents the principles and components that underlie all known signaling processes. It provides undergraduate and graduate students the conceptual tools needed to make sense of the dizzying array of pathways used by the cell to communicate. By emphasizing the common design principles, components, and logic that drives all signaling, the book develops a conceptual framework through which students can understand how thousands of diverse signaling proteins interact with each other in vast interconnected networks. The book first examines the common currencies of cellular information processing and the core components of the signaling machinery. It then shows how these individual components link together into networks and pathways to perform more sophisticated tasks. Many specific examples are provided throughout to illustrate common principles, and provide a comprehensive overview of major eukaryotic signaling pathways.

Semaphorins Receptor And Intracellular Signaling Mechanisms

Author: Gerard Pasterkamp
Publisher: Springer Science & Business Media
ISBN: 9780387709567
Size: 19.39 MB
Format: PDF, Docs
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This book details our progress in understanding the receptor and intracellular signaling mechanisms utilized by semaphorins. It covers the entire semaphorin field from neurosciences to cardiovascular research and beyond, detailing all the latest techniques and results. The comprehensive overview of semaphorin biology and signaling presented in this book allows one to compare semaphorin functions between different biological systems.