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Molecular Biology Of The Cell 5th Ed 2008

Author: Garland Science
Publisher: Bukupedia
ISBN:
Size: 53.78 MB
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In many respects,w e understand the structure of the universeb etter than the workings of living cells. Scientists can calculate the age of the Sun and predict when it will cease to shine, but we cannot explain how it is that a human being may live for eighty years but a mouse for only two. We know the complete genomes equenceso f thesea nd many other speciesb, ut we still cannot predict how a cell will behave if we mutate a previously unstudied gene. Stars may be l0a3 times bigger, but cells are more complex, more intricately structured, and more astonishingp roducts of the laws of physicsa nd chemistry.T hrough heredity and natural selection, operating from the beginnings of life on Earth to the presentd ay-that is, for about 20Voo f the ageo f the universe-living cellsh ave been progressively refining and extending their molecular machinery and recording the results of their experiments in the genetic instructions they pass on to their progeny. With each edition of this book, we marvel at the new information that cell biologists have gathered in just a few years. But we are even more amazed and daunted at the sophistication of the mechanisms that we encounter. The deeper we probe into the cell,t he more we reafizeh ow much remainst o be understood. In the days of our innocence, working on the first edition, we hailed the identification of a single protein-a signal receptol say-as a great step forward' Now we appreciate that each protein is generally part of a complexwith many others, working together as a system, regulating one another's activities in subtle ways, and held in specific positions by binding to scaffold proteins that give the chemical factory a definite spatial structure. Genome sequencing has given us virtually complete molecular parts-lists for many different organisms; genetics and biochemistry have told us a great deal about what those parts are capable of individually and which ones interact with which others; but we have only the most primitive grasp of the dynamics of these biochemical systems, with all their interlocking control loops. Therefore, although there are great achievements to report, cell biologistsf ace eveng reaterc hallengesf or the future. In this edition, we have included new material on many topics, ranging from epigeneticsh, istonem odificationss, mall RNAs,a nd comparativeg enomicst,o geneticn oise,c ytoskeletadl lmamics,c ell-cyclec ontrol, apoptosis,s tem cells, and novel cancer therapies. As in previous editions, we have tried above all to give readers a conceptual framework for the mass of information that we now have about cells. This means going beyond the recitation of facts. The goal is to learn how to put the facts to use-to reason, to predict, and to control the behavior of living systems. To help readers on the way to an active understanding, we have for the first time incorporatede nd-of-chapterp roblems,w ritten by Iohn Wilson and Tim Hunt. These emphasize a quantitative approach and the art of reasoning from experiments.A companion volume, MolecularB iologyo f the CelI,F ifth Edition: TheP roblemsB ook0 SBN9 78-0-8153-4110-9b)y, t he samea uthors,g ivesc omplete answerst o thesep roblemsa nd alsoc ontainsm ore than 1700a dditional problems and solutions. A further major adjunct to the main book is the attached Media DVD-ROM disc. This provides hundreds of movies and animations, including manythat are new in this edition, showing cells and cellular processesin action and bringing the text to life; the disc also now includes all the figures and tables from the main book,p re-loadedin to [email protected] esentationsO. thera ncillariesa vailablefo r the book include a bank of test questions and lecture outlines, available to qualified instructors,a nd a seto f 200f ull-coloro verheadtr ansparencies. Perhaps the biggest change is in the physical structure of the book. In an effort to make the standard Student Edition somewhat more portable, we are providing chapters 2r-25, covering multicellular systems, in electronic (pDF) form on the accompanying disc, while retaining in the printed volume chapters l-20, covering the core of the usual cell biology curriculum. But we should emphasize that the final chapters have been revised and updated as thoroughly as the rest of the book and we sincerely hope that they will be read! A Reference Edition (ISBN9 7s-0-8153-4r11-6c)o, ntainingt he full seto f chaptersa sp rinred pages, is also available for those who prefer it. Full details of the conventions adopted in the book are given in the Note to the Readert hat follows this PrefaceA. s explainedt here,w e have taken a drastic approach in confronting the different rules for the writing of gene names in different species: throughout this book, we use the same style, regardless of speciesa, nd often in defianceo fthe usuals pecies-specifcico nventions. As always,w e are indebted to many people. Full acknowledgmentsfo r scientific help are given separatelyb, ut we must here singleo ut somee xceptionally important contributions: Iulie Theriot is almost entirely responsible for chapters 16 (cytoskeleton)a nd 24 (PathogensI,n fection, and Innate Immunity), and David Morgan likewise for chapter 17 (cell cycle). wallace Marshall and Laura Attardi provided substantialh elp with chapters 8 and 20, respectively,a s did Maynardo lson for the genomicss ectiono f chapter4 ,X iaodongwangf or chapter 18, and Nicholas Harberd for the plant section of Chapter 15. we also owe a huge debt to the staff of Garland science and others who helped convert writers' efforts into a polished final product. Denise schanck directed the whole enterprise and shepherded the wayward authors along the road with wisdom, skill, and kindness. Nigel orme put the artwork into its final form and supervisedt he visuala spectso f the book,i ncluding the backc over,w ith his usual flair. Matthew Mcclements designed the book and its front cover. Emma Jeffcockla id out its pagesw ith extraordinarys peeda nd unflappablee fficiency, d ealingi mpeccablywith innumerablec orrections.M ichaelM oralesm anaged the transformation of a mass of animations, video clips, and other materials into a user-friendly DVD-ROM. Eleanor Lawrence and sherry Granum updatedand enlargedt he glossaryJ. ackieH arbor and SigridM assonk ept us organized. Adam Sendroffkept us aware ofour readers and their needs and reactions. Marjorie Anderson, Bruce Goatly, and sherry Granum combed the text for obscurities, infelicities, and errors. we thank them all, not only for their professional skill and dedication and for efficiency far surpassing our own, but also for their unfailing helpftrlnessa nd friendship:t hey havem adei t a pleasuret o work on the book. Lastly, and with no less gratitude, we thank our spouses, families, friends and colleaguesw. ithout their patient,e ndurings upport,w e couldn ot havep roduced any of the editions of this book. MolecularB iologyo f the Cell BruceA lberts AlexandeJro hnson JulianL ewis Martin Raff Keith Roberts PeteWr alter Withp roblemsb y John Wilson Tim Hunt GarlandS cience Taylo&r FranciGs roup

Molecular Biology Of The Cell

Author: Bruce Alberts
Publisher: Garland Science
ISBN: 9780815341116
Size: 29.58 MB
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Ideal for libraries, laboratories, and researchers, this Reference Edition provides the complete text of Chapters 1-25 in printed format. The Media DVD contains PowerPoint presentations and more than 125 animations, videos, and molecular models.

Molecular Biology Of The Cell

Author: John H. Wilson
Publisher: Garland Pub
ISBN:
Size: 75.71 MB
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Designed to correspond with the first 20 chapters of the fifth edition of "Molecular Biology of the Cell," this workbook contains more than 2,000 problems and their solutions, which also appear on the accompanying CD-ROM.

Cell And Molecular Biology

Author: Gerald Karp
Publisher:
ISBN: 9780470293584
Size: 38.81 MB
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This title is intended for sophomore/junior-level courses in cell biology offered out of molecular and/or cell biology departments. Cell and Molecular Biology gives students the tools they need to understand the science behind cell biology. Karp explores core concepts in considerable depth, and presents experimental detail when it helps to explain and reinforce the concept being explained. This fifth edition continues to offer an exceedingly clear presentation and excellent art program, both of which have received high praise in prior editions.

Molecular Biology And Biotechnology

Author: John M. Walker
Publisher: Royal Society of Chemistry
ISBN: 0854041257
Size: 14.29 MB
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This popular textbook has been revised and updated to provide a comprehensive overview and to reflect the latest developments in this rapidly developing area. Continuing with the broad base style of both current molecular and traditional biotechnology, chapters have been updated to reflect current interest and include new areas such as stem cell technology and important areas in drug discovery such as IP and patents. By presenting information in an easily assimilated form, this book makes an ideal undergraduate text for students of biology and chemistry, as well as to postgraduates.

Physical Biology Of The Cell

Author: Rob Phillips
Publisher: Garland Science
ISBN: 1134111584
Size: 23.64 MB
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Physical Biology of the Cell is a textbook for a first course in physical biology or biophysics for undergraduate or graduate students. It maps the huge and complex landscape of cell and molecular biology from the distinct perspective of physical biology. As a key organizing principle, the proximity of topics is based on the physical concepts that unite a given set of biological phenomena. Herein lies the central premise: that the appropriate application of a few fundamental physical models can serve as the foundation of whole bodies of quantitative biological intuition, useful across a wide range of biological problems. The Second Edition features full-color illustrations throughout, two new chapters, a significantly expanded set of end-of-chapter problems, and is available in a variety of e-book formats.

Using The Biological Literature

Author: Diane Schmidt
Publisher: CRC Press
ISBN: 1466558571
Size: 67.93 MB
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The biological sciences cover a broad array of literature types, from younger fields like molecular biology with its reliance on recent journal articles, genomic databases, and protocol manuals to classic fields such as taxonomy with its scattered literature found in monographs and journals from the past three centuries. Using the Biological Literature: A Practical Guide, Fourth Edition is an annotated guide to selected resources in the biological sciences, presenting a wide-ranging list of important sources. This completely revised edition contains numerous new resources and descriptions of all entries including textbooks. The guide emphasizes current materials in the English language and includes retrospective references for historical perspective and to provide access to the taxonomic literature. It covers both print and electronic resources including monographs, journals, databases, indexes and abstracting tools, websites, and associations—providing users with listings of authoritative informational resources of both classical and recently published works. With chapters devoted to each of the main fields in the basic biological sciences, this book offers a guide to the best and most up-to-date resources in biology. It is appropriate for anyone interested in searching the biological literature, from undergraduate students to faculty, researchers, and librarians. The guide includes a supplementary website dedicated to keeping URLs of electronic and web-based resources up to date, a popular feature continued from the third edition.

Emery S Elements Of Medical Genetics E Book

Author: Peter D Turnpenny
Publisher: Elsevier Health Sciences
ISBN: 0702045055
Size: 75.65 MB
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Master the genetics you need to know with the updated 14th Edition of Emery’s Elements of Medical Genetics by Drs. Peter Turnpenny and Sian Ellard. Review the field’s latest and most important topics with user-friendly coverage designed to help you better understand and apply the basic principles of genetics to clinical situations. Learning is easy with the aid of clear, full-color illustrative diagrams, a wealth of clinical photographs of genetic diseases, multiple-choice and case-based review questions, and end-of-chapter summaries. With this highly visual, award-winning classic in your hands, you have all the genetics knowledge you need for exams or practice. This title includes additional digital media when purchased in print format. For this digital book edition, media content is not included. Get a broad view of medical genetics with a unique three-part structure that looks at the Principles of Human Genetics, Genetics in Medicine, and Clinical Genetics. Visualize the appearance of genetic disorders with a fantastic art program that presents many clinical photos of genetic diseases, and work through complicated ideas with an array of full-color illustrative diagrams. Master the material you need to know with a title preferred by faculty and students alike over the last three decades and awarded the British Medical Association Medial Student Textbook of the Year in 2008. Access to www.studentconsult.com, including 150 USMLE-style multiple choice questions to aid study and self-testing. Apply the latest research with chapters on developmental genetics, cancer genetics, prenatal testing and reproduction genetics, ‘clonal’ sequencing, and more. Understand complex concepts with the help of an increased number of diagrams. Be fully aware of social, ethical, and counseling issues by reviewing an improved section on these topics.

Molecular Cell Biology

Author: Harvey Lodish
Publisher: Macmillan
ISBN: 9780716776017
Size: 51.15 MB
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The sixth edition provides an authoritative and comprehensive vision of molecular biology today. It presents developments in cell birth, lineage and death, expanded coverage of signaling systems and of metabolism and movement of lipids.

Histology

Author: Michael H. Ross
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781767903
Size: 32.75 MB
Format: PDF, Docs
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Now it its Fifth Edition, this best-selling text and atlas is the perfect text for medical, health professions, and undergraduate biology students. It combines a detailed textbook that emphasizes clinical and functional correlates of histology with a beautifully illustrated atlas featuring full-color digital micrographs of the highest quality. This edition includes over 100 new illustrations, more Clinical Correlation boxes on the histology of common medical conditions, and new information on the molecular biology of endothelial cell function. Terminology throughout the text is consistent with Terminologia Anatomica. A powerful interactive histology atlas CD-ROM for students is included with the book and features all of the plates found in the text with interactive functionality.