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The Immunoassay Handbook

Author: David Wild
Publisher: Newnes
ISBN: 0080970389
Size: 41.94 MB
Format: PDF, ePub, Mobi
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The fourth edition of The Immunoassay Handbook provides an excellent, thoroughly updated guide to the science, technology and applications of ELISA and other immunoassays, including a wealth of practical advice. It encompasses a wide range of methods and gives an insight into the latest developments and applications in clinical and veterinary practice and in pharmaceutical and life science research. Highly illustrated and clearly written, this award-winning reference work provides an excellent guide to this fast-growing field. Revised and extensively updated, with over 30% new material and 77 chapters, it reveals the underlying common principles and simplifies an abundance of innovation. The Immunoassay Handbook reviews a wide range of topics, now including lateral flow, microsphere multiplex assays, immunohistochemistry, practical ELISA development, assay interferences, pharmaceutical applications, qualitative immunoassays, antibody detection and lab-on-a-chip. This handbook is a must-read for all who use immunoassay as a tool, including clinicians, clinical and veterinary chemists, biochemists, food technologists, environmental scientists, and students and researchers in medicine, immunology and proteomics. It is an essential reference for the immunoassay industry. Provides an excellent revised guide to this commercially highly successful technology in diagnostics and research, from consumer home pregnancy kits to AIDS testing. www.immunoassayhandbook.com is a great resource that we put a lot of effort into. The content is designed to encourage purchases of single chapters or the entire book. David Wild is a healthcare industry veteran, with experience in biotechnology, pharmaceuticals, medical devices and immunodiagnostics, which remains his passion. He worked for Amersham, Eastman-Kodak, Johnson & Johnson, and Bristol-Myers Squibb, and consulted for diagnostics and biotechnology companies. He led research and development programs, design and construction of chemical and biotechnology plants, and integration of acquired companies. Director-level positions included Research and Development, Design Engineering, Operations and Strategy, for billion dollar businesses. He retired from full-time work in 2012 to focus on his role as Editor of The Immunoassay Handbook, and advises on product development, manufacturing and marketing. Provides a unique mix of theory, practical advice and applications, with numerous examples Offers explanations of technologies under development and practical insider tips that are sometimes omitted from scientific papers Includes a comprehensive troubleshooting guide, useful for solving problems and improving assay performancee Provides valuable chapter updates, now available on www.immunoassayhandbook.com

Immunosensing For Detection Of Protein Biomarkers

Author: Huangxian Ju
Publisher: Elsevier
ISBN: 0081020007
Size: 60.85 MB
Format: PDF, ePub, Docs
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Immunosensing for Detection of Protein Biomarkers not only introduces the principles, methods, and classification of immunoassay, but also presents the latest achievements in areas such as electrochemical immunosensors, nanoprobe-based immunoassay, chemiluminescence immunoassay, electrochemiluminescent immunoassay, multianalyte immunoassay, optical imaging for immunoassay, signal amplification for immunoassay, and so on. In recent years, immunosensing and immunoassay methods have attracted considerable interest due to their applications in different fields, particularly clinical diagnosis. Although a large number of academic papers in immunosensing and immunoassay have been published in different journals recently, it is still a difficult and time-consuming task for researchers, especially those new to the area, to understand the principles, methods, and research progress of immunosensing. Based on the research experience of the authors and their research groups, this book offers readers with new research ideas to develop immunosensing methodology. As a monograph, it offers deeper and more complete coverage than review papers, which only report certain aspects of progress. Grounded in the research experience of Professor Ju’s research group, the book focuses on immunosensing for detection of protein biomarkers, summarizing understanding, research, and practice on immunosensing methodology in detection of protein biomarkers. Presents the latest research and thinking on immunosensing for detection of protein biomarkers Offers current techniques, and looks to the development of new methodologies Offers the latest developments in various aspects of immunosensing, including electrochemiluminescent immunoassay, multianalyte immunoassay, optical imaging immunoassay, and signal amplification immunoassay Offers readers new ideas to research and develop immunosensing methodologies for the future

Clinical Chemistry

Author: Donna Larson
Publisher: Elsevier Health Sciences
ISBN: 1455742163
Size: 10.15 MB
Format: PDF, ePub, Docs
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Gain a clear understanding of pathophysiology and lab testing! Clinical Chemistry: Fundamentals and Laboratory Techniques prepares you for success as a medical lab technician by simplifying complex chemistry concepts and lab essentials including immunoassays, molecular diagnostics, and quality control. A pathophysiologic approach covers diseases that are commonly diagnosed through chemical tests broken down by body system and category such as respiratory, gastrointestinal, and cardiovascular conditions. Written by clinical chemistry educator Donna Larson and a team of expert contributors, this full-color book is ideal for readers who may have minimal knowledge of chemistry and are learning laboratory science for the first time.Full-color illustrations and design simplify complex concepts and make learning easier by highlighting important material.Case studies help you apply information to real-life scenarios."Pathophysiology and Analytes" section includes information related to diseases or conditions, such as a biochemistry review, disease mechanisms, clinical correlation, and laboratory analytes and assays.Evolve companion website includes case studies and animations that reinforce what you ve learned from the book."Laboratory Principles" section covers safety, quality assurance, and other fundamentals of laboratory techniques.Review questions at the end of each chapter are tied to the learning objectives, helping you review and retain the material.Critical thinking questions and discussion questions help you think about and apply key points and concepts."Other Aspects of Clinical Chemistry" section covers therapeutic drug monitoring, toxicology, transplantation, and emergency preparedness.Learning objectives in each chapter help you to remember key points or to analyze and synthesize concepts in clinical chemistry.A list of key words Is provided at the beginning of each chapter, and these are also bolded in the text.""Chapter summaries consist of bulleted lists and tables highlighting the most important points of each chapter.A glossary at the back of the book provides a quick reference to definitions of all clinical chemistry terms. "

Clinical Chemistry

Author: Donna Larson
Publisher: Elsevier Health Sciences
ISBN: 0323292534
Size: 15.20 MB
Format: PDF, ePub, Docs
View: 5586
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Gain a clear understanding of pathophysiology and lab testing! Clinical Chemistry: Fundamentals and Laboratory Techniques prepares you for success as a medical lab technician by simplifying complex chemistry concepts and lab essentials including immunoassays, molecular diagnostics, and quality control. A pathophysiologic approach covers diseases that are commonly diagnosed through chemical tests — broken down by body system and category — such as respiratory, gastrointestinal, and cardiovascular conditions. Written by clinical chemistry educator Donna Larson and a team of expert contributors, this full-color book is ideal for readers who may have minimal knowledge of chemistry and are learning laboratory science for the first time. Full-color illustrations and design simplify complex concepts and make learning easier by highlighting important material. Case studies help you apply information to real-life scenarios. Pathophysiology and Analytes section includes information related to diseases or conditions, such as a biochemistry review, disease mechanisms, clinical correlation, and laboratory analytes and assays. Evolve companion website includes case studies and animations that reinforce what you’ve learned from the book. Laboratory Principles section covers safety, quality assurance, and other fundamentals of laboratory techniques. Review questions at the end of each chapter are tied to the learning objectives, helping you review and retain the material. Critical thinking questions and discussion questions help you think about and apply key points and concepts. Other Aspects of Clinical Chemistry section covers therapeutic drug monitoring, toxicology, transplantation, and emergency preparedness. Learning objectives in each chapter help you to remember key points or to analyze and synthesize concepts in clinical chemistry. A list of key words Is provided at the beginning of each chapter, and these are also bolded in the text. Chapter summaries consist of bulleted lists and tables highlighting the most important points of each chapter. A glossary at the back of the book provides a quick reference to definitions of all clinical chemistry terms.

Molecular Sensors And Nanodevices

Author: John X J Zhang
Publisher: William Andrew
ISBN: 1455776769
Size: 23.36 MB
Format: PDF, Docs
View: 7712
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With applications ranging from medical diagnostics to environmental monitoring, molecular sensors (also known as biosensors, chemical sensors, or chemosensors), along with emerging nanotechnologies offer not only valuable tools but also unlimited possibilities for engineers and scientists to explore the world. New generation of functional microsystems can be designed to provide a variety of small scale sensing, imaging and manipulation techniques to the fundamental building blocks of materials. This book provides comprehensive coverage of the current and emerging technologies of molecular sensing, explaining the principles of molecular sensor design and assessing the sensor types currently available. Having explained the basic sensor structures and sensing principles, the authors proceed to explain the role of nano/micro fabrication techniques in molecular sensors, including MEMS, BioMEMS, MicroTAS among others. The miniaturization of versatile molecular sensors opens up a new design paradigm and a range of novel biotechnologies, which is illustrated through case studies of groundbreaking applications in the life sciences and elsewhere. As well as the techniques and devices themselves, the authors also cover the critical issues of implantability, biocompatibility and the regulatory framework. The book is aimed at a broad audience of engineering professionals, life scientists and students working in the multidisciplinary area of biomedical engineering. It explains essential principles of electrical, chemical, optical and mechanical engineering as well as biomedical science, intended for readers with a variety of scientific backgrounds. In addition, it will be valuable for medical professionals and researchers. An online tutorial developed by the authors provides learning reinforcement for students and professionals alike. Reviews of state-of-the-art molecular sensors and nanotechnologies Explains principles of sensors and fundamental theories with homework problems at the end of each chapter to facilitate learning Demystifies the vertical integration from nanomaterials to devices design Covers practical applications the recent progress in state-of-the-art sensor technologies Includes case studies of important commercial products Covers the critical issues of implantability, biocompatibility and the regulatory framework