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The Leukemia Lymphoma Cell Line Factsbook

Author: Hans G. Drexler
Publisher: Academic Press
ISBN: 0080535445
Size: 19.39 MB
Format: PDF, Docs
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This book represents an essential reference manual for all of the well-characterized leukemia-lymphoma cell lines currently available. It provides the most important facts, using the succinct and user-friendly format that has made the FactsBooks so popular with scientists and clinical researchers. Introductory chapters provide background and perspective for culturing malignant hematopoietic (blood forming) cell lines. These chapters are followed by over 400 comprehensive individual entries. Each cell line entry highlights essential clinical, immunological, genetic, and functional features and includes a comprehensive listing of references. Key Features * the full spectrum of malignant cell lines from all hematopoietic cell lineages * sister cell lines and relevant subclones * clinical data: patient, diagnosis, treatment status, and specimen source * authentication of derivation and availability * immunophenotype * cytogenetic karyotype * translocations and fusion genes * receptor gene rearrangements and genetic alterations * cell cultures aspects: establishment, medium, doubling time, growth * cytochemical profile * cytokine production and response to cytokines * proto-oncogene and transcription factor expression/alteration * functional features: differentiation induction, heterotransplantability * special unique features * key references

Cancer Cell Culture

Author: Simon P. Langdon
Publisher: Springer Science & Business Media
ISBN: 9781588290793
Size: 52.94 MB
Format: PDF, ePub, Mobi
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Expert researchers describe in detail their most productive and up-to-date methods for growing cancer cells in the laboratory. There are methods to characterize and authenticate cell lines, to isolate and develop specific types of cancer cells, and to develop new cell line models. Functional assays are provided to evaluate clonogenicity, cell proliferation, apoptosis, adhesion, migration, invasion, senescence, angiogenesis, and cell cycle parameters. Other methods permit the modification of cancer cells for transfection, development of drug resistance, immortalization, and transfer in vivo; the co-culture of different cell types; and the detection and treatment of contamination.

The T Cell Receptor Factsbook

Author: Marie-Paule Lefranc
Publisher: Elsevier
ISBN: 9780080542645
Size: 62.15 MB
Format: PDF
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The T Cell Receptor FactsBook contains entries on all the 176 functional variable, diversity, joining, and constant regions of the human T cell receptor, including alpha, beta, gamma, and delta loci. Introductory chapters summarize information of T cell receptor chain synthesis, chromosomal location, and an overview of the human T cell receptor loci.

The Immunoglobulin Factsbook

Author: Marie-Paule Lefranc
Publisher: Academic Press
ISBN: 0080574475
Size: 66.64 MB
Format: PDF, ePub, Mobi
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The FactsBook series has established itself as the best source of easily accessible and accurate facts about protein groups. Books in the series use an easy-to-follow format and are meticulously researched and compiled by experts in the field. The Immunoglobulin FactsBook is the first published reference for all 203 human functional and ORF immunoglobulin genes. It is complete and standardized and employs nomenclature approved by the HUGO Nomenclature Committee.

The Nuclear Receptor Factsbook

Author: Vincent Laudet
Publisher: Gulf Professional Publishing
ISBN: 9780124377356
Size: 35.30 MB
Format: PDF, ePub
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The FactsBook Series has established itself as the best source of easily accessible and accurate facts about protein groups. They use an easy-to-follow format and are researched and compiled by experts in the field. This Factsbook is devoted to nuclear receptors. The first section presents an introduction and describes the mode of action of the receptors in general. The second section of the book contains detailed entries covering each type of receptor. Entries provide information on: Nomenclature and structure Isolation DNA binding properties Ligands Expression Target genes Knockouts Disease association Gene structure, promoter and isoforms Chromosomal location Amino acid sequences Key references

Acute Leukemias Ix

Author: Wolfgang Hiddemann
Publisher: Springer
ISBN: 9783540439714
Size: 38.71 MB
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Acute Leukemias IX provides an extended and thorough overview of recent developments in cell biology and experimental therapy for acute leukemias. Following the tradition of the Acute Leukemias series since 1987, this book bridges the gap between basic research and clinical studies and emphasizes that both aspects are equally necessary to achieve improvements, not only in understanding the disease but also in providing better therapy. As a forum for world-wide activities in the field of acute leukemias the volume contains invaluable contributions that provide the reader with new, previously unpublished information.